Does Off-Label Topiramate Support Weight Management?
“Doctors will find out that certain medications do certain things effectively, and then will start using them for that purpose,” Dr. Rogers says. “Part of the reason that topiramate may not be FDA-approved for weight loss is that although research has found that it can be effective, researchers don’t yet fully understand how it achieves this weight loss effect.”
A doctor might prescribe topiramate for weight loss if other options haven’t worked, have led to severe side effects, or are too costly for the patient, she adds.
“It all comes down to what insurance will cover, what works, and what the patient can afford,” Rogers says. “If a patient also lives with migraine, a doctor might choose topiramate to try to achieve both effects with a single medication.”
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