MERCEDES SCHLAPP (GUEST): And it’s not just Minnesota where the indoctrination of little kids is occurring. Here’s YouTube star Ms. Rachel and Israeli-hating Hamas apologists joining New York City’s communist mayor Zohran Mamdani, to help him promote free child care to two year-olds.
…
SCHLAPP: Ms. Rachel. Oh my goodness, Foldi.
MATTHEW FOLDI (GUEST): I actually thought you could call her MS-13 Rachel —
SCHLAPP: I do call her MS-13 Rachel.
FOLDI: I mean, this woman is literally — the only reason that I’ve heard of this person — obviously, I don’t have kids — is because she’s a terrorist-loving, mentally ill psychopath who should not be allowed near children. The video I thought, honestly, that we were going to watch is where she and Zohran are crying in the classroom, and that’s — I thought that was just a segment so that they could teach the children of New York City what is going to happen when they are set on fire by an illegal immigrant on the free busses that New York City can’t afford that they want to try and happen. There’s a serious problem. This is like textbook radicalization, not this specific clip. But Ms. Rachel is so crazy, she would find a home — she’d have to wear a burqa and be fully covered, obviously, in Gaza, teaching little Palestinians to kill Jews.
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For most people, the blood pressure benefits of GLP-1 drugs come primarily from weight loss itself. In general, larger weight losses lead to larger drops in blood pressure, particularly at higher doses, says Dr. Bahrainwala.
Weight loss also significantly improves the body’s response to insulin, says Sarah Ackah, MD, an endocrinologist at the Ohio State University Wexner Medical Center in Columbus. When insulin doesn’t work properly, blood sugar rises, blood vessels become damaged, and blood pressure becomes harder to control.
In addition to improving insulin sensitivity and lowering blood sugar, losing weight also reduces inflammation throughout the body, all of which adds up to less strain on the cardiovascular system, says Dr. Ackah.
Additionally, weight loss can improve or even resolve conditions that worsen hypertension, such as sleep apnea and chronic joint pain that limits physical activity, says Bahrainwala. When people become more mobile and metabolically healthier, blood pressure often improves as well.
In practice, the changes in blood pressure can be significant. Bahrainwala has seen patients who lost substantial weight on GLP-1 therapy and needed their blood pressure medications reduced or stopped altogether.
“I’ve had to work actively with these patients to cut back their blood pressure medications because of the improvements caused by the GLP-1 weight loss,” she says.
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CORPUS CHRISTI, Texas – Former Uvalde CISD officer Adrian Gonzales is in court again Tuesday morning as emotional testimony continues from yesterday.
Gonzales is being charged with 29 counts of abandoning or endangering a child. Prosecutors say he didn’t act quickly enough during the 2022 massacre, where 19 students and two teachers were killed.
Testimony is set to continue at 9 a.m. on Tuesday.
Surviving teacher’s testimony
The backstory:
On Monday, one teacher’s recollection of that day was flagged for discrepancies before the judge ultimately decided to strike her comments from the record. Soon after, emotional testimony was given by a teacher injured in the shooting at Robb Elementary School in Uvalde.
Arnulfo Reyes, expected to continue testimony on Tuesday, was a teacher working inside the school when the gunman walked into his classroom and opened fire. Reyes survived by playing dead but none of his students survived.
Jurors heard emotional testimony on Monday in the trial for a former Uvalde police officer accused of failing to protect students. Arnulfo Reyes was a teacher working inside Classroom 111 when the gunman walked in and opened fire at Robb Elementary School in Uvalde. He told jurors he survived by playing dead. None of his students survived.
Reyes described gruesome testimony describing that the shooter shot at him, striking him in the arm. That gunman then came back into his classroom and taunted Reyes, before shooting him again in the back.
No questions were asked about Adrian Gonzales during the teacher’s testimony, but the defense did point out that Reyes did not get a notification from the school’s emergency alert system or hear an announcement from their intercom system.
Images from inside Robb Elementary School
Dig deeper:
Last week, powerful new images of the destruction of Robb Elementary School were shown to the juror depicting the day of the May 2022 shooting. Prosecutors presented dozens of photos of new evidence throughout the school, documenting the damage left behind.
Witness testimony was heard from former teachers who were sheltered in classrooms, parents of children who lost their lives and district employees who were on the scene during the mass shooting at Robb Elementary School.
Forensic experts and federal agents also weighed in on video from the shooting and evidence examined at the scene. Texas Ranger and bullet trajectory analyst Kevin Wright testified that many of the bullets traveled from the outside of the building, into classrooms and to adjoining rooms.
Testimony from victim’s parent
The mother of one shooting victim, 9-year-old Eliana Garcia, gave her recollection of the day of the shooting. Jennifer Garcia said Eliana had asked to come home early that day, but Jennifer told her to stay to participate in an end-of-year pizza party with her class.
Eliana would have turned 10 on June 4, just a week after the shooting.
Jennifer Garcia, the mother of Ellie Garcia, recalls the day of the shooting at Robb Elementary. Garcia remembers being told about the shooting and waiting to find out what had happened to her daughter.
Big picture view:
Nearly 400 officers responded to the school on May 24, 2022. More than 70 minutes passed before a tactical team entered, killing the shooter.
ElevenLabs, the AI voice generation startup, crossed $330 million in annual recurring revenue (ARR), CEO Mati Staniszewski said in an interview with Bloomberg.
“Really, what this [growth in ARR] shows is that trajectory across the company. We started the company in 2022 and launched the first product in 2023. It took us 20 months to reach $100 million in ARR, 10 months to reach $200 million, and five months to reach the current number,” he said.
Staniszewski mentioned that both Fortune 500 companies and startups are adopting its voice agent technology, which uses company data and knowledge bases to power customer support and customer experience interactions. In a separate post on X, the company noted that enterprises have deployed its technology to handle more than 50,000 calls per month.
MINNEAPOLIS – (WBAP/KLIF) – The state of Minnesota and Twin Cities sue the federal government to stop the massive immigration crackdown, as protests grow in the streets of Minneapolis after a resident was shot and killed last Wednesday by an ICE agent.
The lawsuit in federal court accompanies a temporary restraining order to stop the enforcement action or limit the operation.
Department of Homeland Security says it’s surging more than 2,000 immigration officers into Minnesota with another 1,000 ordered in this week. ICE reports making more than 2,000 arrests in the city since the operation began last month.
The suit alleges Operation Metro Surge violates federal law because it is arbitrary and capricious, as other states are not seeing similarly large crackdowns. The operation in Minneapolis is the largest deployment of ICE and supporting federal officers to date. The Trump administration says it’s about fighting fraud, though the lawsuit says ICE agents have no expertise in combatting fraud in government programs. The fraud cases referred too began in 2018, with many convicted of fraud and serving time.
The lawsuit states the federal government is really targeting Minnesota over politics, which it says violates the First Amendment.
(Copyright, All Rights Reserved, WBAP/KLIF 2026)
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Each week, at a warehouse in Brooklyn, volunteers sort through thousands of pounds of fabric from colorful cotton scraps to unused bolts of linen and silk.
Tagle: “What a lot of people don’t realize is that along the course of the production of garment making, there is a lot of waste that happens along the way.”
Camille Tagle is cofounder of FABSCRAP. The nonprofit partners with clothing brands to reuse and recycle textile waste – including fabric samples, prototype designs, and scraps left over after cutting and sewing.
Some of the material is sold online or in person at the organization’s store.
Tagle: “Maybe, you know, somebody wants to make a top or a dress out of one of our fabrics. People also use it for arts and crafts.”
Other material gets shredded into a product that’s used for insulation, carpet padding, and more.
Tagle says reusing and recycling textile waste helps keep material out of landfills, where it emits climate-warming methane as it decomposes.
And it reduces the amount of new material that needs to be produced in the first place – which cuts down on carbon pollution at all stages of the supply chain.
So FABSCRAP is helping reduce the climate impact of fashion, one scrap at a time.
Reporting credit: Sarah Kennedy / ChavoBart Digital Media
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In his room, 19-year-old Cody Nester toggles between Grindr profiles on his phone.
As he senses chemistry with a match, he knows he has to flag something that could be a deal breaker.
“Did you see on my profile that I’m HIV positive?” he writes.
The reply arrives instantly.
“You’re disgusting. I don’t know why you’re on here.” Seconds later, the profile disappears, suggesting Nester is blocked.
“He went out of his way to say that. People could at least be more aware, ask questions, and understand the reality [of living with HIV] instead of attacking us,” Nester told Uncloseted Media.
(Valerie Chaparro for Uncloseted Media)
“I would say 95% of people respond that way,” says Nester, who lives in Hollywood, Florida, and works at a Mexican restaurant. “The entire conversation is going fine. They’re down to meet up and then right when I mention [HIV], it’s always, ‘Oh no, never mind.’”
Some other messages he’s received include:
“You’ll never get anything in your life.” “Why don’t you die?” “Why are you on here?”
More often, it’s silence, a cold “No” or a sudden block.
“It’s like you’re a white fish in a school of black fish,” he says. “You’re immediately the odd one out.”
Even though Nester’s undetectable status makes it impossible for him to transmit HIV to partners during sex, he experiences stigma around HIV, something which nearly 90% of Americans agree still exists, according to a 2022 GLAAD report. And a survey shared in 2019 found that 64% of respondents would feel uncomfortable having sex with someone living with HIV, even on effective treatment. The emotional cost of this stigma is a significant barrier to intimacy and can result in a loss of self-esteem, fear of disclosure and suicidal thoughts.
What the science says — and why it doesn’t seem to matter
(Valerie Chaparro for Uncloseted Media)
“The fear comes from antiquated ideas around HIV,” says Xavier A. Erguera, senior clinical research coordinator at University of California, San Francisco’s (UCSF) Division of HIV, Infectious Diseases & Global Medicine. “A lot of people who are newly diagnosed still fear it’s a death sentence. Even though we have medications now to treat it effectively, and it’s basically a chronic condition, people haven’t caught up.”
Since 1996, antiretroviral therapies have developed to where they can suppress the virus to levels so low that it is undetectable in the blood, and thus not able to be transmitted to sexual partners. This is known as Undetectable = Untransmittable, or U=U. According to a Centers for Disease Control and Prevention report from 2024, 65% of HIV-positive cases are virally suppressed.
Another line of defense is pre-exposure prophylaxis (PrEP), which reduces the risk of acquiring HIV from sexual intercourse by roughly 99% when taken as prescribed. Approved by the Food and Drug Administration in 2012, the medication launched as a once-a-day pill and was hailed as a breakthrough as it transformed the sex lives of gay men, which had been shaped by decades of fear about HIV complications and about where AIDS came from.
“Internal logic doesn’t reflect what we know scientifically,” says Kim Koester, associate professor in the Department of Medicine at UCSF. “I was very optimistic when PrEP came out. The drug works, so why wouldn’t everyone use it?”
Even with PrEP use on the rise, less than 600,000 Americans used it in 2024, and Koester says skepticism and judgments about taking the drug persist.
“The phobia is pervasive,” Koester told Uncloseted Media. “People believe that others get the disease because of their lifestyle. … PrEP was supposed to be the antidote to the threat of HIV, reduce the anxiety, and make you more open to who you are and the sex you want. It’s supposed to be liberating. It is part of the answer. But it’s not enough. We don’t have enough people using PrEP for it to make the dent in the stigma we need.”
According to a 2023 study of seven informants living with HIV, public stigma stems from problematic views from society that those living with HIV are “a dangerous transmission source,” “disgraceful” and “violators of social and religious norms who have committed deviant behavior.”
Laramie Smith, assistant professor of Global Public Health at the University of California, San Diego, says this stigma is unwarranted and fueled by misunderstanding:
“With today’s treatments, it shouldn’t be a life-altering identity shift. It should be no different than, ‘I have diabetes.’ If you’re virally suppressed, it shouldn’t matter whether you’re friends with someone, whether you’re sleeping with someone—the science shows us that.”
How HIV phobia shows up online
(Valerie Chaparro for Uncloseted Media)
Nester, who contracted HIV last year from a Grindr hook-up who insisted he was negative, says he is just starting to accept his diagnosis. “I didn’t go back on the apps for a long time after that. It messed with my mental health … realizing I’d have to take medication for the rest of my life.”
Since he started dating again this year, returning to apps like Grindr and Sniffies, he has faced a new normal. He tries to do everything “right” and disclose his status early. Even on his Grindr profile, he identifies as “poz,” slang for HIV-positive.
Still, he says most people ghost him once they find out. “The second I bring it up, it’s ‘No,’” says Nester. “The amount of discrimination you get … it’s always the same pattern. … People don’t know, and they don’t want to know. It messes with you.”
This discrimination may be fueled by a deprioritization of HIV awareness programs across the country. Earlier this month, the U.S. State Department did not commemorate World AIDS Day for the first time in 37 years. HIV prevention programs have been slashed, especially in conservative districts, and only 25 states and D.C. require both HIV and sex education. In many states, health curricula often lag behind current science and omit teaching about PrEP, gay sex and concepts like U=U. Research shows that Gen Z is currently the least educated generation about HIV.
“I could go all day explaining HIV, but people don’t want to listen,” says Nester, who is part of Gen Z. “People don’t want to learn about it; they just want to avoid it.”
HIV anxiety and public stigma shaped by history
(Valerie Chaparro for Uncloseted Media)
Even in more progressive areas, stigma still exists. Damian Jack, a 45-year-old from Brooklyn, remembers sitting in an exam room in 2009 as a doctor explained how low his T-cell count was, which is a hallmark of HIV infection.
“I started hysterically crying,” he told Uncloseted Media. “HIV meant death. That’s what I thought.”
In 1981, when Jack was 1 year old, the first reports of a mysterious and deadly immune deficiency syndrome, which would later be named AIDS, appeared in the U.S. Growing up, Jack saw countless terrifying images of men on their deathbeds with Kaposi sarcoma, the purple lesions the media once called “gay cancer.” Public misinformation and fearmongering spread ideas that AIDS was a disease that “only gay men and drug users get.” And politicians often equated it with homosexuality and moral failure, calling it a “gay plague.” It wasn’t until September 1985, four years after the crisis began and thousands had died, that President Ronald Reaganfirst publicly mentioned AIDS.
Decades later, the emotional residue of that era and the shame associated with the virus lingers.
Hours after learning of his diagnosis, Jack faced his first encounter with rejection. He already had a date planned that night, and his doctor and friends encouraged him to go.
They had a great time until the date asked him: “Are you negative or positive?”
He told the truth.
“It was just understood there wouldn’t be a second date,” says Jack. “I remember thinking, ‘This is how dating is going to be now.’ I felt so anxious telling guys. It followed me everywhere. I don’t think that anxiety ever truly goes away.”
The emotional impact of HIV stigma
(Valerie Chaparro for Uncloseted Media)
For those who are HIV-negative, experts say that “stigma’s whole design is to ‘other.’”
“The ‘us versus them’ creates that false sense of safety when it comes to HIV,” says Smith. “If I can believe that someone did something to deserve their diagnosis, and I’m not that [kind of person], then I’m safe.”
“If I’m undesirable, and that’s what those messages are communicating, that threatens your sense of safety, your sense of belonging and the fundamental desire we all have to be loved,” Smith says. “And that starts to reinforce the thinking that ‘I am not worthy. This virus that I have means that I’m not lovable. I am not safe showing up among other men.’”
“I pretend it doesn’t hurt, but some things do sting a little bit,” Nester says. “You start thinking, ‘Am I really that disgusting? Am I really that singled out?’”
When public stigma turns inward
(Valerie Chaparro for Uncloseted Media)
“Internalized stigma is what occurs when applying the stereotypes about who gets HIV, the prejudice, the negative feelings, onto yourself,” says Smith.
In 2024, 38% of people living with HIV reported internalized stigma. And studies show that it can predict hopelessness and lower quality of life, even when people are engaged in care or virally suppressed.
Internalized stigma can also affect how people practice safe sex and communicate about the virus. A 2019 survey of men who have sex with men found that individuals who perceived greater community-level stigma were less likely to be aware of—and use—safer-sex functions available on dating apps, such as HIV-status disclosure fields, as well as sexual health information and resources.
“[HIV phobia] is probably the most intense, subvert bigotry I think you could experience,” Joseph Monroe Jr., a 48-year-old living in the Bronx, told Uncloseted Media.
On dating apps, men have messaged him things like, “You look like you’ve got that thing” and “Go ahead and infect someone else.”
Monroe Jr. has also dealt with misinformed people who rudely opine about how he contracted the virus: “Who fucked you? That’s how you got it, right?” people will say to him.
“You end up internalizing all these stereotypes about who gets HIV—that you were promiscuous, that you didn’t care about yourself, that you did something wrong,” says Smith. “You carry that in, and then you have to relearn: ‘No, I didn’t. This is just a health condition.’”
What HIV acceptance looks like and raising awareness
(Valerie Chaparro for Uncloseted Media)
For those living with HIV, acceptance feels far away.
“You’re living under this threat of HIV and the threat that others find you threatening. It inhabits you socially and sexually,” Koester says. “People are hunkering down. Not putting themselves out there and having a mediocre quality of life. To have a sense of empowerment, you have to be legitimate and seen in the world and it’s hard to do that with the stigma that exists.”
Researchers say the path forward lies as much in conversation as in medicine.
Koester says she talks about HIV and PrEP anywhere she can, including in salons, cafes and restaurants. “Whenever I get into a cab with someone, I’m going to bring up HIV so the driver gets accustomed to hearing about it. … We have a long way to go in terms of exposure and awareness and every little bit helps.”
Part of this lies in increasing awareness through targeted marketing campaigns. PrEP is still profoundly misunderstood outside major urban centers, with uneven uptake among minority groups and usage gaps in the bible belt. And a 2022 U.S. survey found that 54.5% of people living with HIV didn’t know what U=U meant, and less than half of Americans agree that people living with HIV who are on proper medications cannot transmit the virus.
While eradicating stigma is slow, there is hope for acceptance.
Years after Jack’s diagnosis, in 2021, he told a man he was on a third date with that he was HIV-positive but undetectable. His date’s reply was almost casual:
“Oh—is that it? I thought you were going to say you had a boyfriend or something. I’m on PrEP. You’re fine.”
“It felt so good to hear him say that and accept me,” says Jack. “I was like, ‘This is my person. You’re my person.’” One year later, they got married. Back in Florida, 19-year-old Cody Nester isn’t feeling this acceptance. He still scrolls past profiles that read “Only negative guys” and tries to ignore the hateful messages.
“It still hurts, but I know it’s coming from fear,” he says. “I wasn’t too informed about HIV before I got it. … When I got it, I really jumped into the rabbit hole and began to learn. I really do think [HIV and stigma] is because people are not knowledgeable. … When people don’t know details, they tend to get scared.”
Additional Reporting by Nandika Chatterjee.
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When one of Adam Burkhammer’s foster children struggled with hyperactivity, the West Virginia legislator and his wife decided to alter their diet and remove any foods that contained synthetic dyes.
“We saw a turnaround in his behavior, and our other children,” said Burkhammer, who has adopted or fostered 10 kids with his wife. “There are real impacts on real kids.”
The Republican turned his experience into legislation, sponsoring a bill to ban seven dyes from food sold in the state. It became law in March, making West Virginia the first state to institute such a ban from all food products.
The bill was among a slew of state efforts to regulate synthetic dyes. In 2025, roughly 75 bills aimed at food dyes were introduced in 37 states, according to the National Conference of State Legislatures.
Chemical dyes and nutrition are just part of the broader “Make America Healthy Again” agenda. Promoted by Health and Human Services Secretary Robert F. Kennedy Jr., MAHA ideas have made their deepest inroads at the state level, with strong support from Republicans — and in some places, from Democrats. The $50 billion Rural Health Transformation Program — created last year as part of the GOP’s One Big Beautiful Bill Act to expand health care access in rural areas — offers incentives to states that implement MAHA policies.
Federal and state officials are seeking a broad swath of health policy changes, including rolling back routine vaccinations and expanding the use of drugs such as ivermectin for treatments beyond their approved use. State lawmakers have introduced dozens of bills targeting vaccines, fluoridated water, and PFAS, a group of compounds known as “forever chemicals” that have been linked to cancer and other health problems.
In addition to West Virginia, six other states have targeted food dyes with new laws or executive orders, requiring warning labels on food with certain dyes or banning the sale of such products in schools. California has had a law regulating food dyes since 2023.
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Most synthetic dyes used to color food have been around for decades. Some clinical studies have found a link between their use and hyperactivity in children. And in early 2025, in the last days of President Joe Biden’s term, the Food and Drug Administration outlawed the use of a dye known as Red No. 3.
Major food companies including Nestle, Hershey, and PepsiCo have gotten on board, pledging to eliminate at least some color additives from food products over the next year or two.
“We anticipate that the momentum we saw in 2025 will continue into 2026, with a particular focus on ingredient safety and transparency,” said John Hewitt, the senior vice president of state affairs for the Consumer Brands Association, a trade group for food manufacturers.
“The state laws are really what’s motivating companies to get rid of dyes,” said Jensen Jose, regulatory counsel for the Center for Science in the Public Interest, a nonprofit health advocacy group.
Andy Baker-White, the senior director of state health policy for the Association of State and Territorial Health Officials, said the bipartisan support for bills targeting food dyes and ultraprocessed food struck him as unusual. Several red states have proposed legislation modeled on California’s 2023 law, which bans four food additives.
“It’s not very often you see states like California and West Virginia at the forefront of an issue together,” Baker-White said.
Although Democrats have joined Republicans in some of these efforts, Kennedy continues to drive the agenda. He appeared with Texas officials when the state enacted a package of food-related laws, including one that bars individuals who participate in the Supplemental Nutrition Assistance Program — SNAP, or food stamps — from using their benefits to buy candy or sugary drinks. In December, the U.S. Department of Agriculture approved similar waivers sought by six states. Eighteen states will block SNAP purchases of those items in 2026.
There are bound to be more. The Rural Health Transformation Program also offers incentives to states that implemented restrictions on SNAP.
“There are real and concrete effects where the rural health money gives points for changes in SNAP eligibility or the SNAP definitions,” Baker-White said.
In October, California Gov. Gavin Newsom signed a bill that sets a legal definition for ultraprocessed foods and will phase them out of schools. It’s a move that may be copied in other states in 2026, while also providing fodder for legal battles. In December, San Francisco City Attorney David Chiu sued major food companies, accusing them of selling “harmful and addictive” products. The lawsuit names specific brands — including cereals, pizzas, sodas, and potato chips — linking them to serious health problems.
Kennedy has also blamed ultraprocessed foods for chronic diseases. But even proponents of the efforts to tackle nutrition concerns don’t agree on which foods to target. MAHA adherents on the right haven’t focused on sugar and sodium as much as policymakers on the left. The parties have also butted heads over some Republicans’ championing of raw milk, which can spread harmful germs, and the consumption of saturated fat, which contributes to heart disease.
Congress has yet to act on most MAHA proposals. But state lawmakers are poised to tackle many of them.
“If we’re honest, the American people have lost faith in some of our federal institutions, whether FDA or CDC,” said Burkhammer, the West Virginia lawmaker. “We’re going to step up as states and do the right thing.”
Trump filed a lawsuit in December over the way the BBC edited a speech he gave on Jan. 6, 2021. The claim, filed in a Florida court, seeks $5 billion in damages for defamation and $5 billion for unfair trade practices.
The speech took place before some of Trump’s supporters stormed the U.S. Capitol as Congress was poised to certify President-elect Joe Biden’s victory in the 2020 election that Trump falsely alleged was stolen from him.
The BBC had broadcast the documentary — titled “Trump: A Second Chance?” — days before the 2024 U.S. presidential election. It spliced together three quotes from two sections of the 2021 speech, delivered almost an hour apart, into what appeared to be one quote in which Trump urged supporters to march with him and “fight like hell.” Among the parts cut out was a section where Trump said he wanted supporters to demonstrate peacefully.
The broadcaster has apologized to Trump over the edit of the Jan. 6 speech. But the publicly funded BBC rejected claims it had defamed him. The furor triggered the resignations of the BBC’s top executive and its head of news.
Papers filed Monday with Florida’s Southern District court say the BBC will file a motion to dismiss the case on the basis that the court lacks jurisdiction, the court venue is “improper” and Trump has “failed to state a claim.”
The broadcaster’s lawyers will argue that the BBC did not create, produce or broadcast the documentary in Florida and that Trump’s claim the documentary was available in the U.S. on streaming service BritBox is not true.
It will also argue that Trump has failed to “plausibly allege” the BBC acted with malice in airing the documentary.
The BBC is asking the court to “to stay all other discovery” — the pretrial process in which parties gather information — pending a decision on the motion to dismiss. The discovery process could require the BBC to hand over reams of emails and other documents related to its coverage of Trump.
If the case continues, a 2027 trial date has been proposed.
“As we have made clear previously, we will be defending this case,” the BBC said Tuesday in a statement. “We are not going to make further comment on ongoing legal proceedings.”
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Artificial intelligence is moving quickly into drug discovery as pharmaceutical and biotech companies look for ways to cut years off R&D timelines and increase the chances of success amid rising cost. More than 200 startups are now competing to weave AI directly into research workflows, attracting growing interest from investors. Converge Bio is the latest company to ride that shift, securing new capital as competition in the AI-driven drug discovery space heats up.
The Boston- and Tel Aviv–based startup, which helps pharma and biotech companies develop drugs faster using generative AI trained on molecular data, has raised a $25 million oversubscribed Series A round, led by Bessemer Venture Partners. TLV Partners and Vintage Investment Partners also joined the round, along with additional backing from unidentified executives at Meta, OpenAI, and Wiz.
In practice, Converge trains generative models on DNA, RNA, and protein sequences then plugs them into pharma and biotech’s workflows to speed up drug development.
“The drug-development lifecycle has defined stages — from target identification and discovery to manufacturing, clinical trials, and beyond — and within each, there are experiments we can support,” Converge Bio CEO and co-founder Dov Gertz said in an exclusive interview with TechCrunch. “Our platform continues to expand across these stages, helping bring new drugs to market faster.”
So far, Converge has rolled out customer-facing systems. The startup has already introduced three discrete AI systems: one for antibody design, one for protein yield optimization, and one for biomarker and target discovery.
“Take our antibody design system as an example. It’s not just a single model. It’s made up of three integrated components. First, a generative model creates novel antibodies. Next, predictive models filter those antibodies based on their molecular properties. Finally, a docking system, which uses physics-based model, simulates the three-dimensional interactions between the antibody and its target,” Gertz continued. The value lies in the system as a whole, not any single model, according to the CEO. “Our customers don’t have to piece models together themselves. They get ready-to-use systems that plug directly into their workflows.”
The new funding comes about a year and a half after the company raised a $5.5 million seed round in 2024.
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Since then, the two-year-old startup has scaled quickly. Converge has signed 40 partnerships with pharmaceutical and biotech companies and is currently running about 40 programs on its platform, Gertz said. It works with customers across the U.S., Canada, Europe and Israel and is now expanding into Asia.
The team has also grown rapidly, increasing to 34 employees from just nine in November 2024. Along the way, Converge has begun publishing public case studies. In one, the startup helped a partner boost protein yield by 4 to 4.5X in a single computational iteration. In another, the platform generated antibodies with extremely high binding affinity, reaching the single-nanomolar range, Gertz noted.
image credits: converge bio
AI-driven drug discovery is experiencing a surge of interest. Last year, Eli Lilly teamed up with Nvidia to build what the companies called the pharma industry’s most powerful supercomputer for drug discovery. And in October 2024, the developers behind Google DeepMind’s AlphaFold project won a Nobel Prize in Chemistry for creating AlphaFold, the AI system that can predict protein structures.
When asked about the momentum and how it is shaping Converge Bio’s growth, Gertz said that the company is witnessing the largest financial opportunity in the history of life sciences and the industry is shifting from “trial-and-error” approaches to data-driven molecular design.
“We feel the momentum deeply, especially in our inboxes. A year and a half ago, when we founded the company, there was a lot of skepticism,” Gertz told TechCrunch. That skepticism has vanished remarkably quickly, thanks to successful case studies from companies like Converge and from academia, he added.
Large language models are gaining attention in drug discovery for their ability to analyze biological sequences and suggest new molecules, but challenges like hallucinations and accuracy remain. “In text, hallucinations are usually easy to spot,” the CEO said. “In molecules, validating a novel compound can take weeks, so the cost is much higher.” To tackle this, Converge pairs generative models with predictive ones, filtering new molecules to reduce risk and improve outcomes for its partners. “This filtration isn’t perfect, but it significantly reduces risk and delivers better outcomes for our customers,” Gertz added.
TechCrunch also asked about experts like Yann LeCun, who remain skeptical about using LLMs. “I’m a huge fan of Yann LeCun, and I completely agree with him. We don’t rely on text-based models for core scientific understanding. To truly understand biology, models need to be trained on DNA, RNA, proteins, and small molecules,” Gertz explained.
Text-based LLMs are used only as support tools, for example, to help customers navigate literature on generated molecules. “They’re not our core technology,” Gertz said. “We’re not tied to a single architecture. We use LLMs, diffusion models, traditional machine learning, and statistical methods when it makes sense.”
“Our vision is that every life-science organization will use Converge Bio as its generative AI lab. Wet labs will always exist, but they’ll be paired with generative labs that create hypotheses and molecules computationally. We want to be that generative lab for the entire industry,” Gertz said.
Great Job Kate Park & the Team @ TechCrunch Source link for sharing this story.